Parasitologia hungarica

Author(s): Horváth, Gy., Albert, M. & Kemenes, F.
Title: The pathogenicity of Trypanosoma equiperdum to different rodents. III. Susceptibility of the guinea pig (Cavia porcellus)
Title: A Trypanosoma equiperdum különböző rágcsálókkal szembeni fertőzőképessége. III. A tengerimalac (Cavia porcellus) fogékonysága
Year: 1990
Volume: 23
Pages: 19-26.

Abstract: A total of 30 mature guinea pigs were inoculated intraperitoneally with 1-1.5 × 10000000 Trypanosoma equiperdum. The trypanosomes were demonstrable from the guinea pigs only for 3 weeks; after that time the possibility of individual detection decreased. At postinoculation (PI) weeks 5-6 three guinea pigs died of subacute, and at PI weeks 20-22 another three guinea pigs died of chronic trypanosomosis. The disease seen in these latter 3 animals corresponded to the pathological entity of dourine. These studies suggest that the guinea pig is moderately resistant to T. equiperdum and is a suitable model for the experimental reproduction of chronic dourine.
Keywords: Trypanosoma equiperdum, guinea pig, moderate susceptibility, characteristic lesions of dourine

Journal: Parasitologia Hungarica
Journal abbreviation:
ISSN: 0303-688X
Publisher: Ameko Kft, Budapest
Editor(s): K. Murai, É., Thoma, A., Bajomi, D. & Lotterhof, E.