Parasitologia hungarica

Author(s): Szénási, Zs., Mecseki, R., Lukács, K., Urbán, E., Rákos, K., Ozsvár, Z. & Nagy, E.
Title: Analysis of the serological results of toxoplasma screening of pregnant women in Szeged with special regard to the year 1995
Title: A szegedi terhes nők toxoplasma szűrése szerológiai módszerekkel és az eredmények elemzése, különös tekintettel az 1995-ös évre
Year: 1996-1997
Volume: 29-30
Pages: 17-26.

Abstract: A general screening program was organized in the region of Szeged for the early detection of congenital toxoplasmosis in pregnant women. Between 1987 and 1995, all pregnant women in that region (a total of 19,985 persons) were screened by modern serological methods: 115 of them were found to belong to the category of being “suspicious of acute toxoplasmosis”. All these pregnant women and their newborn (n = 115) were appropriately monitored both clinically and serologically (CFT, anti-P30 ELISA IgG, IgA and IgM determination, PCR amplification and Western blot analysis). Furthermore, appropriate treatment was immediately started both in the mothers suspicious of “acute” toxoplasmosis and in their newborn. No case of congenital toxoplasmosis has been detected among the infants and children so far. Thus, we consider the program highly successful for congenital toxoplasmosis screening. An analysis of serological data of the 2,091 pregnant women screened in 1995 is also presented and discussed.
Keywords: Toxoplasma gondii, congenital toxoplasmosis, serological screening, fetomaternal treatment, prevalence rate, “acute” vs “chronic” infection, analysis of age groups, prevention of fetal infection

Journal: Parasitologia Hungarica
Journal abbreviation:
ISSN: 0303-688X
Publisher: Magyar Parazitológusok Társasága, Budapest
Editor(s): K. Murai, É., Thoma, A., Gubányi, A. & Tajti, T. Zs.